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In absolute terms, the primary composite occurred in 0.7% of GLP-1 users and 1.8% of never-users during days 91365, corresponding to approximately one fewer event per 100 patients

Prescribing GLP-1s in a psychiatric context isn't just a metabolic decision it's a psychiatric one

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We also evaluated acute treatment with tirzepatide, a dual GLP-1/gastric inhibitory peptide (GIP) receptor agonist, and retatrutide, a triple GIP/GLP-1/glucagon receptor agonist, to determine whether broader receptor activity would differentially influence alcohols subjective effects
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