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2023;24(3):2959

The injector is a prefilled pen device that is used to inject the medication under the skin once a week

The most common issues are gastrointestinal: nausea, vomiting, diarrhea, constipation, acid reflux, stomach pain and discomfort

In this Review, the authors discuss neuromodulation therapies in relation to current knowledge of the nerve circuitry, provide insights into possible mechanisms and explore reasons for limited success and how effectiveness might be improved.

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