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After excluding the exploratory cohort and participants from a site terminated for Good Clinical Practice noncompliance, 615 participants were included in the main efficacy analysis

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Taken together, these studies strongly support that DAG as a key intermediate of TAG synthesis from fatty acids has central modulation and potential therapeutic values in IR

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Moreover, high adiposity contributes to elevated serum estrogen levels, which, in excess, can promote tumor development by causing DNA damage, stimulating angiogenesis, and fostering cellular proliferation [19]

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At its core, it is just a schedule that tells you how much medication to take each week and when to increase that amount

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