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Description
Exendin-4 (100 nM) decreased IFN- -induced signal transducer and activator of transcription-1 (STAT1), which is important for CXCL10 expression in the pancreatic beta-cell line, MIN6 cells, and human islets
Based on TRIUMPH-4's results and the completed TRIUMPH-1 general obesity trial (28.3% weight loss in 2,339 patients, May 2026), Eli Lilly is expected to submit a New Drug Application in Q4 2026

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