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If significant declines are observed, doses should be adjusted

Starting January 1, 2026 , several major insurance providers, including Blue Cross Blue Shield (BCBS), Cigna, Harvard Pilgrim, and UnitedHealthcare, will implement changes to their coverage of GLP-1 medications

maltodextrin (MDX) on breath hydrogen (a marker of intestinal fermentation), plasma SCFAs, gut hormones, insulin and blood glucose concentrations as well as appetite in RYGB patients

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The paradigm for treating people with obesity has often been to recommend lifestyle changes, and then if they develop diabetes or another metabolic condition, to treat them with metformin, insulin, or GLP-1 drugs, says study senior and corresponding author Andrew Stokes, associate professor of global health