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In the early diabetes group, both agents significantly suppressed aortic plaque formation compared with control, while modestly improving glycemia and lipid levels

Here we revisit the actions of GLP-1, discuss new insights refining cellular localization of GLP-1R expression, and integrate recent data to refine our understanding of how and where GLP-1 acts to control inflammation, cardiovascular function, islet hormone secretion, gastric emptying, appetite, and body weight.

Learn how retatrutide, a triplereceptor weightloss drug in clinical trials, works on GLP1, GIP, and glucagonand what early research shows.