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Description
Starting a GLP-1 medication requires slow dose titration to minimize gastrointestinal side effects

American family physician 94 , 106113 (2016)
Sustainable weight loss and health improvement require a holistic approach

ICERs 2023 framework similarly carves out special analyses: Ultrarare diseases : For therapies affecting 20m/year in any of the first three years should trigger mandatory patient access schemes to contain costs ( [23] )

gastroparesis, poorly controlled diabetes mellitus, end-stage renal disease) and some medications (e.g
