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Much anticipated Phase II results in obesity for Amgens GLP-1 agonist/GIP antagonist showed up to 20% weight loss, but without detailed data the drugs competitiveness is hard to ascertain.

The GLP1-RAs vs sodium-glucose cotransporter-2 (SGLT-2) inhibitors cohort included new users of GLP-1 RAs (n=83,464) or SGLT-2 inhibitors (n=78,366), and the GLP1-RAs vs dipeptidyl peptidase-4 (DPP-4) inhibitors cohort included new users of GLP-1 RAs (n=108,322) or DPP-4 inhibitors (n=55,411)

This is because there is less physical activity leading to less bowel movement

GLP1 adoption is expanding, but a startstop user base is accelerating existing shifts in how consumers eat and how food brands innovate, according to Numerator.

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