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Another important white space is represented by the emergence of comorbidity-driven positioning of oral obesity drugs, which allows marketing such medicines as treatment not only for weight loss but also for obesity associated with type 2 diabetes, cardiovascular risks, metabolic syndrome, and MASH

In their statement to JAMA, William J

Our study, which included a larger and more diverse real-world population with a longer follow-up duration, demonstrated significant psychiatric risks

doi: 10.1016/0026-0495(66)90156-9 [DOI] [PubMed] [Google Scholar] 11
They have narrow therapeutic windows and are sensitive to absorption changes
