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Researchers are currently conducting larger Phase 3 trials to evaluate: Long-term effectiveness Safety Cardiovascular outcomes Weight maintenance after treatment Until these studies are completed and reviewed by regulatory agencies, Retatrutide remains an investigational medication

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They adjusted for factors including gender, ethnicity, use of concurrent metformin, seasonality, and smoking status

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These rates compare favorably with the Phase 2 discontinuation rates (10-17%), likely reflecting the improved dose-escalation schedules used in Phase 3