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If you reduce the dose after they plateau somewhere, theres a risk of having an increased appetite, increased cravings, and regaining weight, she said

The results showed that in the SUSTAIN 3, 7, and 10 trials, nausea/vomiting during dose escalation or throughout treatment contributed minimally ( 65 years), and baseline cardiovascular risk profile (prior myocardial infarction or stroke vs no prior MI or stroke, and established cardiovascular disease vs CV risk factors alone, including chronic kidney disease)

Additionally, it has been demonstrated that short-acting GLP-1RAs improved endometrial function in animal models [110]

Tirzepatide (Mounjaro for type 2 diabetes, Zepbound for weight management) is an FDA-approved dual GIP/GLP-1 receptor agonist that reduces appetite and slows gastric emptying

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