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In major clinical trials, such as the landmark STEP 1 trial published in the New England Journal of Medicine , a once-weekly injection of semaglutide 2.4 mg resulted in an average body weight reduction of roughly 14.9% over 68 weeks

WASHINGTON (TNND) GLP-1 medications have transformed the way doctors treat obesity in adults but as demand grows, a new question is emerging: how young is too young to use these drugs

They note, however, that there are promising signs that we may be able to develop medications to help, such as a monoclonal antibody already in the pipeline that may be able to offset lean-muscle loss

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These findings were substantiated by MS-based proteomics analyses in which we observed a more pronounced response to treatment with GLP-1MK-801 compared with either monotherapy (Fig