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(2024) 326:E52836

Although this umbrella review attempted to comprehensively summarize the current published meta-analyses and analyze the related health outcomes, some emerging research topics, due to being in the experimental phase and lacking support from multiple primary studies, may have been overlooked

Published phase 2 obesity research evaluated once-weekly dose groups, including 1 mg, 4 mg, 8 mg, and 12 mg targets

Providers could consider prescribing oral or subcutaneous semaglutide for approved indications if appropriate, since there was lack of evidence to support significant risk of cholelithiasis seen in one meta-analysis

Injecting Toujeo when you meant to inject a GLP-1 drug could cause severe hypoglycemia, especially at insulin doses