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The disparity between the risk and incidence results might also reflect the difficulties in researching cancer outcomes in communities with low overall incidence, where conclusive results necessitate large sample numbers and long-term data

SGLT2 inhibitor users had the highest rates of hypertension and cardiovascular disease, whereas women prescribed GLP-1R agonists were more likely to be obese or suffer from polycystic ovarian syndrome (PCOS)

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doi: 10.1186/s12933-017-0553-3

Here is the complete picture: Beyond FDA criteria, a legitimate physician evaluation will also consider your current medication list (some drug interactions exist), kidney and liver function, mental health history, and your specific weight loss goals