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It is certainly possible that individuals with overweight or obesity who take semaglutide may experience depressive symptoms or suicidal ideation or behavior, but the data suggest that persons not taking semaglutide in the placebo group in this study - are equally likely to experience these conditions, said Gregory Brown, PhD, a study co-author and Director of the Penn Center for the Prevention of Suicide at the Perelman School of Medicine
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Drugs acting on the monoaminergic and opioid systems, such as bupropion-naltrexone and bupropion-zonisamide, are also being studied
