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Weight loss on a lower starting dose typically progresses more gradually than at higher maintenance doses, but the trajectory remains downward for most patients

This includes Novo's Ozempic, which contains the active ingredient semaglutide and is approved to treat Type 2 diabetes

They can be combined with other therapies and are crucial for integrated care of IBS

The mean change in body weight from baseline to week 104 was -15.2% in the semaglutide group (n = 152) versus -2.6% with placebo (n = 152), for an estimated treatment difference of -12.6 %-points (95% confidence interval, -15.3 to -9.8

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