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However, previous studies have found that DPP-4 can be regulated by inflammatory factors such as signal transducer and activator of transcription 1 (STAT1), hepatocyte nuclear factor-1 (HNF-1), interleukin-12 (IL-12), and tumor necrosis factor- (TNF-) [33,34,35]

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102 However, it should be noted that publications demonstrating the cardiovascular benefits of GLP-1 or its analogs have utilized supraphysiological dosages

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The semaglutide transformation tends to be steady and progressive