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Research shows that GLP-1 medications such as semaglutide show promise for better kidney function, reduced inflammation throughout the body, and a healthier heart, says Kushner

When starting GLP-1 medications, doctors usually begin with a low dose and increase it slowly over several weeks or months to reduce side effects, especially nausea and stomach upset

Nat Med 28(3):591598

They all also work very similarly in the body to make patients feel as if they are fuller for longer, making it much easier to maintain a calorie deficient diet

Even skinny guys like us, you start to hit your 40s and 50s and you go, wow, the weight's coming on in a way it didn't when I was in my 20s and 30s