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It should also recognize that obesity is a chronic medical condition, not a short-term character flaw

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Receptor desensitization : Over time, GLP1 receptors may become less responsive to consistent drug exposure, reducing the appetite-suppressing effect

Additionally, GLP1R expression showed no significant impact on overall survival in cancers such as esophageal squamous cell carcinoma, colon cancer, head-neck squamous cell carcinoma, renal papillary cell carcinoma, hepatocellular carcinoma, lung adenocarcinoma, ovarian cancer, and pancreatic cancer

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