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Miyazono K, Heldin C-H
10.1161/hh1701.095716
Therefore, an increased quantity of adipose tissue in individuals with obesity creates an increase in estrogen concentrations, primarily estrone
Pfizer reported that while the overall frequency of liver enzyme elevations across the over 1,400 participant safety database of danuglipron was in line with approved agents in the class, a single asymptomatic participant in one of the dose-optimization studies experienced potential drug-induced liver injury that resolved after discontinuation of danuglipron
Lancet 394, 15191529
