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While the recent phase 3 trial for orforglipron was specifically for type 2 diabetes and not weight loss, the study found that patients who took the drug lost considerable weight

Digital health platforms were already set up to prescribe online, ship medications directly to patients, drive patient engagement, and operate outside of traditional insurance systems

Bacterial translocation (BT) in cirrhosis

JARDIANCE was used as monotherapy in one trial and as add-on therapy in four trials [see Clinical Studies (14.1)]

The clinical hold applies to all ongoing clinical studies under the IND, including the Phase III HERO trial (AVK-101-301) evaluating ARD-101 for the treatment of hyperphagia in patients with PWS