glp 1 drugs and fertility GLP-1 Receptor Agonists, Restoration, Reproductive Safety in Women of Reproductive Age: A Narrative Review GLP-1 Drugs and PCOS -

Novo-Nordisk A/S, Eli Lilly And Company, Sanofi, AstraZeneca, Pfizer Inc., Amgen, Inc., and Innovent Biologics, Inc

Recently, the introduction of highly effective glucagon-like peptide-1 (GLP-1) receptor agonists has led to increased utilization of obesity medications in this population

Not approved for diagnostic, therapeutic, or medical applications

In conclusion, SAR425899 demonstrated strong interactions at the GLP1R, but no clear occupancy at the GCGR

Beyond these metabolic benefits, accumulating evidence indicates that GLP-1RAs exert immunomodulatory effects, including suppression of pro-inflammatory cytokines, enhancement of regulatory T-cell function, and improvements in adipose tissue and gut-derived immune signaling