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Exercise helps to burn calories and improves overall metabolic health to complement the effects of the medication

The disease affects approximately 1 million adults in the United States, according to the National MS Society, with varying clinical presentations including relapsing-remitting MS (RRMS), secondary progressive MS (SPMS), and primary progressive MS (PPMS)

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The STEP 5 trial provides the more encouraging long-term picture

Finally, tirzepatide may influence key transcription factors involved in lipid metabolism, such as SREBP-1c and PPAR-/, and by improving systemic insulin sensitivity and promoting weight loss, it could push hepatocytes toward a less lipogenic gene expression profile [34]