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Because of the GI effects, caution is advised in patients with severe gastroparesis (e.g., long-standing diabetic gastroparesis) GLP-1 RAs can worsen gastric emptying delays and are generally not recommended in that scenario

Understanding Semaglutide: the Science Behind Weight Loss Within months, Sarah saw dramatic weight loss, ultimately losing over 50 pounds

Ozempic also comes in prefilled autoinjector pens containing 4 doses of semaglutide (one month's worth of medicine)

Below is a general comparison of average retail prices for a one-month supply based on common dosages

The company filed for marketing approval of their semaglutide biosimilar for the treatment of T2D with the National Medical Products Administration (NMPA) in April 2024, and this is expected to amplify clinical development of semaglutide biosimilars from domestic manufacturers in the next two to three years