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GLP-1 & GIP therapy targets GLP-1 and glucagon receptors on pancreatic beta cells, boosting insulin release
Out-of-pocket costs start at $149 per month and go up to $349 for higher doses, according to material an Eli Lilly spokesperson shared with Scientific American
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Contrave works on brain chemistry instead, produces a more modest 5 to 8 percent average, but comes without the GI side effects, injection requirement, or cost barriers that keep some patients away from GLP-1s
