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A meta-analysis comparing clinical effects of short- or long-acting GLP-1 receptor agonists versus insulin treatment from head-to-head studies in type 2 diabetic patients

CMAJ 192 , E875E891 (2020)

It involves altered nerve signaling, not local immune response

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Additionally, altered levels of satiety hormones and the change in the rate of gastric emptying might play pivotal roles (3)
