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Generally, the ARC is responsible for transmitting leptin signals to the hypothalamus and other brain regions for regulating the energy balance and metabolic homeostasis [14]

Also, those who are pregnant or nursing, planning to become pregnant, living with disordered eating, have a personal or family history of certain cancers, or have experienced angioedema, should not take GLP-1 agonists

KCCQ-CSS questionnaire: 23-item instrument that quantifies heart failure-related symptoms (frequency, severity, and recent changes), physical function, quality of life, and social function

This flattens postprandial glucose spikes and help control blood sugar

Suggested Protocol: Athletes cannot rely on thirst