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Tirzepatide, for example, activates C/EBP alpha, which in turn upregulates expression of the tight junction protein claudin-1, thereby keeping the blood-brain barrier intact and functional
Here are some of the most surprising and significant benefits of GLP-1s that are reshaping modern medicine
Sulfonylureas: a new look at old therapy
McMurray, J
Further downstream, specific transcription factors such as Skn1a (or POU class 2 homeobox 3 [POU2F3]) or achaete-scute family BHLH transcription factor 1 (Ascl1) are thought to control which exact cell type is finally developing [65,66]
