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Because GLP-1 pricing now varies by drug, dose, formulation, and whether a patient is in an introductory or maintenance phase, its helpful to consider a range of current prices

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have designed and synthesized highly constrained GLP-1 analogs containing two or three lactam bridges between Glu i and Lys i +4 that were placed simultaneously to stabilize the both helical structures in the N- and C-terminal regions