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Wegovy is designed to treat obesity in children and adults and is also used to treat adults who want to lose weight

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Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist

Options include energy-based skin tightening devices using radiofrequency or ultrasound, biostimulator injectables that support collagen remodeling, and, for more significant laxity, surgical body contouring procedures

Clinical Evidence: Muscle Preservation in Trials Phase 3 Lean Mass Data Retatrutide (23.9% weight loss): Lean mass loss: ~5.2% of body weight Lean mass as % of total loss: 21.8% Fat loss: 78.2% of total weight lost Tirzepatide (20.9% weight loss): Lean mass loss: ~6.8% of body weight Lean mass as % of total loss: 32.5% Fat loss: 67.5% of total weight lost Translation : At 220 lbs body weight with 26 lbs weight loss: Retatrutide achieves 2.5x better muscle preservation than semaglutide