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This estrogen decline can cause vaginal dryness, particularly in perimenopausal and postmenopausal women

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Since obesity is a major risk factor for both OA and diabetes, this has led to the exploration of GLP-1RA as a potential treatment for OA due to its weight loss and anti-inflammatory properties

Fatty Liver Disease (MASLD/MASH): Reduction of liver fat by ~ 82-86%
However, it has since been shown that -arrestins can also function to activate signalling cascades 9,10
