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1,2 In the pancreas, the enzyme prohormone convertase (PC) 2 processes the prohormone proglucagon to glucagon

Water-rich options such as cucumber, tomatoes, watermelon and soups can contribute to overall fluid intake while providing nutrients and helping maintain satiety in smaller portions

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The researchers thought that combining that mechanism with GLP-1s effect of suppressing appetite could be an especially potent approach, and GLP-1 could also offset glucagons effect of raising blood sugar

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