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Glucose-dependent insulinotropic polypeptide a new link in the development of obesity

Tirzepatide administration led to a significant reduction in GLP-1R expression in the cortex and hippocampus, as evidenced by decreased phosphorylation of protein kinase A (PKA) substrates at Thr197

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Seven of these trials are expected to report results in 2026

GI side effects like diarrhea deplete magnesium rapidly
