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NOTE (1) Commonly observed laboratory findings: In pre-hepatic condition, indirect bilirubin and urine urobilinogen are very high, with normal SGPT and serum alkaline phosphatase

This is often referred to as the "GLP-1 trap": employees lose weight quickly, but the underlying behaviors don't change so as soon as the medication stops, the weight comes back

Future research should aim to unravel the precise molecular mechanisms underlying these weight-independent benefits, enabling the development of new therapies that harness these anti-inflammatory pathways and potentially bypass the limitations of current interventions

But even as he calls for more robust data on long-term outcomes and safety in older adults, Batsis says that his skepticism regarding the benefits of these drugs has decreased over the past few years

Less common but more serious side effects of GLP-1 agonists include: pancreatitis, an inflammation of the pancreas that causes abdominal pain gastroparesis, in which movement of food out of the stomach is slowed or stopped bowel obstruction, a blockage that keeps food from passing through the intestines gallstone attacks and bile duct blockage