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Semaglutide slows gut motility through its GLP-1 receptor effects throughout the gastrointestinal tract

Those taking tirzepatide, achieved an additional 18.4% WL from randomisation to 72 weeks compared to those taking placebo who experienced weight regain of 2.5% [48]

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4) PEGylation modification: Increase the size of drug molecules and slow down enzyme degradation