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Relative contraindications include severe renal impairment, gastroparesis, recent bariatric surgery, and pregnancy or breastfeeding
10.1016/j.kint.2022.08.012 [DOI] [PubMed] [Google Scholar] 12
Nausea is one of the most frequently reported side effects of GLP-1 agonist medications
Nevertheless, the broad spectrum of targets for GLP-1 RAs also introduces certain risks and side effects
For those wondering about results without exercise, losing weight on semaglutide without exercise is possible, though outcomes tend to be better with at least some physical activity
