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Description
GLP-1 was discovered in the 1980s, with the first GLP-1 receptor agonist (exenatide) approved by the FDA in 2005 for diabetes

Patients who experience substantial weight loss or excellent glycemic control with minimal side effects are more likely to continue long-term therapy

19 Substitution with Aib 8 hardly influences the cAMP activity and substitution with D-Ala 8 induces little or no change in the affinity or cAMP activity

Hopkins, B

& Queva, C
