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Gastrointestinal distressnausea, vomiting, constipationis most frequent, especially early on

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285,286 Collectively, GLP-1 RAs integrate metabolic, anti-inflammatory, and neuroprotective mechanisms, representing a promising strategy to promote healthier aging, enhance cognitive resilience, and extend healthspan across multiple organ systems

But given the importance of the US market, the worlds leading generic-drug makers are already eyeing it

The heterodimerization and interaction with different binding partners will be discussed in a later section