asa guidelines glp-1 🔸 Should RAs be continued preprocedurally? 🔸 Who should stop a GLP-1 RA preoperatively? 🔸 Which patients should have their procedures postponed? Read: https://doi.org/10.1097/01.ASM.0001125664.22893.9f Indications for GLP-1/GIP RA Summary

A recent study demonstrated that GLP-1 enhances preingestive satiety through hypothalamic circuits in both mice and humans, with GLP-1R-expressing neurons in the dorsomedial hypothalamus (DMH) emerging as key candidates for encoding this satiety signal [24]

doi: 10.1002/oby.23374

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45,46 Oral semaglutide was further investigated against placebo with regard to its cardiovascular safety (PIONEER 6) in patients considered to be at high cardiovascular risk, safety and efficacy in patients with moderate renal impairment (PIONEER 5), and safety and efficacy as an add-on therapy to insulin-treated patients (PIONEER 8)

Patients often experience enhanced tolerability through the gradual therapeutic introduction, with a notably reduced incidence of gastrointestinal side effects