glp 1 new indications What's next for GLP-1 innovation: A primer on the race reshaping pharma and chronic disease care Frontiers | GLP−1 receptor agonists

11 Modulation of invariant natural killer T (iNKT) cells by GLP-1RAs was another mechanism demonstrated to improve psoriasis

Appetite Regulation: GLP-1 acts on the brain to help regulate appetite and promote a feeling of fullness, which can reduce overall calorie consumption

Alongside the anticipated CV safety of many of these agents, evidence for certain sodiumglucose transporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have revealed potential cardioprotective effects in patients with T2D who are at high risk of CVD events

J Biol Chem (2009) 284(16):10890900.10.1074/jbc.M807994200 47 Pacheco-PantojaELDillonJPWilsonPJFraserWDGallagherJA

Several additional GLP-1 receptor agonists also display neuroprotective properties in preclinical AD models