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In XIGDUO XR-treated patients with a diagnosis or strong suspicion of lactic acidosis, prompt hemodialysis is recommended to correct the acidosis and remove accumulated metformin (metformin HCl is dialyzable, with a clearance of up to 170 mL/min under good hemodynamic conditions)

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People who have preferences like following a vegan diet may also need special consideration, as they can also be on GLP-1 medications

One of the most surprising findings, according to Gler, was how these drugs [activated] the emotion center and [engaged] the reward mechanisms in the brain. When the researchers gave mice a standard diet, which Gler described as the equivalent of salads for humans, the drugs had no effect

Prioritize protein on GLP-1 The goal here should be about 1.2 grams of protein per day per kilogram of body weight (or 0.55 grams of protein per pound of body weight), Christen says