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This study showed a mean weight reduction of 10%, and significant reductions in triglyceride, total cholesterol, and LDL-C levels of 25%, 11%, and 11% respectively [32]

You may have found your optimal maintenance dose when: Weight loss is consistent at 0.5-1.0% per week Side effects are manageable and not significantly impacting quality of life Appetite is well controlled without feeling starved Energy levels are stable and adequate for daily activities and exercise Blood glucose and other metabolic markers are improving If these criteria are met at 8mg, there is no clinical obligation to push to 12mg

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A 45-degree angle works well if you have thinner tissue, while a 90-degree (perpendicular) angle suits those with thicker subcutaneous fat layers