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This approach has shown better outcomes for weight maintenance in real-world settings compared to sudden discontinuation

For more information about the effects of GLP-1 drugs on colonoscopy and endoscopy prep, we sat down with Jennifer Christie, MD, director of the Division of Gastroenterology and Hepatology in the CU Department of Medicine.

Subcutaneous injections into abdominal, thigh, and upper arm sites deliver GLP-1 medications through the same tissue layer in clinical trials that demonstrated weight loss and metabolic benefits

Current Status (2026) Retatrutide remains under clinical investigation and is progressing through large Phase 3 trials for obesity and related metabolic conditions