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However, if reactions become increasingly severe, widespread, or are accompanied by signs of infection or allergic response, contact your GP or diabetes specialist nurse for review

These symptoms typically subside after the first few weeks of treatment

Additional analyses were conducted at individual study level or pooled across 5 SURPASS trials

Not surprisingly, a specific GLP-1 receptor antagonist, exendin [939] amide, accelerates gastric emptying in individuals without diabetes with proportional rises in plasma glucose and insulin (17), indicating that physiological postprandial concentrations of GLP-1 are sufficient to slow gastric emptying substantially

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