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Earlier medications such as topiramate and sympathomimetic agents like phentermine have shown short-term weight loss benefits, but their use is often restricted due to side effects including fatigue, memory impairment, insomnia, and elevated cardiovascular risk

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Reiman EM, Caselli RJ, Yun LS, Chen K, Bandy D, Minoshima S, et al

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[DOI] [PubMed] [Google Scholar] 196.Amerio A, Stubbs B, Odone A, Tonna M, Marchesi C, Nassir Ghaemi S

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