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Amy Schroeder Principal Research Scientist | July 9, 2025 Current Landscape Overview Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) are an emerging drug class that are mostly indicated to improve glycemic control in patients with type 2 diabetes mellitus (T2D) and reduce body weight
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With orforglipron offering additional advantages such as the elimination of strict pre-dosing requirements, potential lower cost, and easier storage, it will be important to see whether these features lead to even greater adherence, says Priya Jaisinghani, a diabetes and obesity medicine specialist at NYU Langone
doi: 10.1152/ajpheart.00554.2011, PMID: [DOI] [PubMed] [Google Scholar] 65
Switching between medications requires careful dose conversion
