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The gut hormone glucagon-like peptide-1 produced in brain: Is this physiologically relevant

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Metabolic profile of the hippocampus of Zucker diabetic fatty rats assessed by in vivo 1H magnetic resonance spectroscopy

The combination of exenatide with the sodiumglucose co-transporter 2 (SGLT2) inhibitor, dapagliflozin, was investigated in the DURATION-8, phase III clinical trial which demonstrated a degree of synergy between the two agents, with improvements in short- and long-term glycaemia and weight loss exceeding either agent alone (144)
