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Reasonable triggers include: vomiting or diarrhea persisting beyond 24-48 hours, inability to keep down fluids, symptoms of dehydration, muscle weakness interfering with function, or mental status changes

Its a decision that should be made in partnership with a medical professional who understands the nuances of these powerful medications

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This is because extra fat tissue produces an enzyme (aromatase) that turns testosterone into estrogen, which can leave men with lower testosterone