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Description
The main enzyme involved, dipeptidyl peptidase-4 (DPP-4) also known as CD26, cleaves off the two N-terminal residues resulting in GLP-1 (9-36 amide) which is inactive or acts as an inhibitor at the GLP-1 receptor (23)

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Systematic rotation of injection sites prevents repeated trauma to the same area

While the compounded options that have been filling the gap arent FDA-approved (a red flag), they have been available at much lower pricesmaking their imminent illegality a potential access issue

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