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Kidney function: Estimated GFR, BUN, creatinine
The combined treatment of sCT and liraglutide, especially when administered in a stepwise manner, produced greater body weight loss, reduced adiposity and decreased plasma leptin levels compared to individual monotherapies and vehicle in DIO rats
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Tirzepatide overcomes these limitations by simultaneously activating both GIPR and GLP-1R, thereby harnessing their complementary mechanisms of action [25]
2025 doi: 10.1001/jamaophthalmol.2024.6058
